Science and CBD

Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most prominent active ingredients from the female hemp plant (Cannabis sativa L.). While the combination of extracts rich in THC and CBD has established itself thanks to its analgesic and antispastic effects in patients with multiple sclerosis, the application profile of CBD is still at the beginning of its exploration.

Today, CBD is legal in the UK and Europe, and you can now order the best CBD products online at the best online suppliers such as JustBob.shop.

Besides, you can learn more all about  CBD and its effects by clicking here.

CBD for a better sleep

In a double-blind study with 15 patients suffering from insomnia and taking 40, 80 and 160 mg CBD or placebo, a significant increase in the duration of sleep was shown with 160 mg. 40 and 80 mg and the placebo showed no corresponding effect.

In a double-blind study, 24 patients (18 diagnosed with MS) were treated with THC, CBD, the 1:1 mixture of the same, and placebo. The individual dosages ranged from 2.5 to 120 mg per day. The results for CBD were unremarkable concerning the parameter sleep quality.

In a crossover study with 34 patients with chronic pain, THC, CBD, the 1:1 mixture of the same and placebo were examined. The individual dosage ranged from 1 to 33 sprays (at 2.5 mg THC, 2.5 mg CBD or 2.5 mg THC and 2.5 mg CBD) per day. THC, CBD, and combination showed a significant effect on sleep quality. The number of patients who slept well was 55% for THC and CBD (p<0.001), 43% for THC (p<0.001), 37% for CBD (p<0.05) and 17% for placebo. Doses of CBD ranged from 1 to 31 puffs (3-78 mg); the median was about 8 sprays (20 mg).

CBD for soothing pains

In a crossover study with 34 patients with chronic pain, THC, CBD, the 1:1 mixture of the same and placebo were examined: THC and the combination of THC and CBD showed a significant effect compared to placebo – CBD, however, did not. The dosages were individual and ranged from 1-33 sprays (each with 2.5 mg THC or CBD or with 2.5 mg THC and 2.5 mg CBD) per day.

A double-blind study evaluated 24 patients with untreatable neurogenic pain (18 with MS). THC, CBD, a 1:1 mixture of the same and a placebo served as medication. Doses ranged from 2.5 to 120 mg per day. In the case of pain, a significant effect was found for both THC and CBD, but this is only based on the results of 12 patients with CBD. The results for CBD were unremarkable for other parameters such as cramps or sleep quality.

CBD and tobacco 

In a double-blind study with 24 smokers, CBD was compared to placebo. The test drugs could be inhaled ad libitum. Within a week, the number of cigarettes smoked with CBD administration – but not with the placebo – was significantly reduced by around 40%.

CBD and its compatibility with the human organism

Undesirable effects occasionally occur with doses of up to 20 mg. However, at doses of 20 mg/kg body weight, they are observed very frequently.

Based on the latest and largest controlled CBD study, the following can be stated for this high dosage. Adverse events were observed in 93% of the CBD group and 75% of the placebo group. 75% of the adverse events in the CBD group were likely related to the study compared to 36% in the placebo group.

Common adverse events (with >10% frequency) in the CBD group were: vomiting, fatigue, fever, upper respiratory tract infection, decreased appetite, convulsions, lethargy, drowsiness, and diarrhea. In the CBD group, 8 patients discontinued the study due to adverse events, in the placebo group, there was 1 patient.

Final thoughts

More studies are ongoing worldwide, but you can already buy the best CBD products online from the best suppliers, such as JustBob.shop.